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Liver Support For Dogs


Veterinarians prescribe liver supplements for dogs and cats to protect and improve their liver function. Ingredients like S-adenosylmethionine, milk thistle silymarin and bile acid, are scientifically proven to improve glutathione levels, increase antioxidant activity, and accelerate the repair and regeneration of liver cells. Ask Ariel has the best liver supplements for dogs containing these same trusted ingredients that support detoxification and improve liver function.

Supplements For Elevated Liver Enzymes in Dogs

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Liver Supplements For Dogs



Special SAMe is the best liver supplement for dogs. It is a powerful antioxidant that is scientifically proven to reduce elevated liver enzymes. S-adenosylmethionine supports the liver by supplementing metabolic activity. Backed by scientific research, this powerful antioxidant has been shown in research studies to detoxify the liver and promote cell regeneration.





LypoZyme For Pets is a tasteless enzyme supplement that improves the digestion of fats and proteins. It’s gentle enough for a tiny pet and effective for larger pets. Liver disease in dogs is often accompanied by digestive problems such as diarrhea and acid stomach. LypoZyme relieves digestive symptoms associated with liver disease in pets.





Power Probiotic is the best probiotic for pets! Backed by scientific research, this powerful multi-strain formula promotes the growth of good bacteria that support healthy liver function and digestion. Pure and natural, Power Probiotic does not contain any fillers. Many pets love the taste of the Power Probiotic!




Liver & Gallbladder Support contains a blend of 10 ingredients that are scientifically proven to promote liver detoxification, increase glutathione levels, and protect liver tissue. Liver & Gallbladder Support contains amino acids, Vitamin A, ox bile and inositol to promote fat metabolism; an herbal blend of milk thistle, artichoke and beet powder to protect the liver against toxins and stimulate regeneration of damaged liver cells. When considering ursodiol alternatives for dogs, Ask Ariel's Liver & Gallbladder Support can help to improve gallbladder function and bile flow. It can help detoxify your pet by helping to flush medications and environmental pollutants and toxins.




Pancreatitis & Liver Support Kit provides comprehensive liver support for dogs and contains three supplements that work synergistically: Power Probiotic, LypoZyme and Liver & Gallbladder Support to improve digestion, support liver and gallbladder health and reduce gastric distress.



  • Helps dogs detoxify naturally
  • Backed by science
  • Relieves digestive symptoms and indigestion
  • Excellent for pets with elevated liver enzymes and liver cancer


  • Purrfect Pet CoQ10 is an excellent antioxidant and anti-inflammatory. Kaneka Ubiquinol™ can help to reduce oxidative stress and inflammation in the liver and improve mitochondrial respiration. Studies also indicate that the improved cellular respiration can help to regenerate the liver and may help to reverse tissue damage due to liver disease.



    What Does Your Dog's Liver Do?


    The liver is the main filtering system for your pet's body similar to what your oil filter does for your car. Keeping it clean will help ensure your pet's blood is properly detoxified. Everything your dog eats, breathes or comes into contact with is filtered through your dog's liver to be processed and eliminated.

    Your dog's liver performs many critical functions:

    • Metabolism of fats, protein and carbohydrates
    • Filtering of harmful substances from the blood (e.g., toxins and/or medications)
    • Storage of vitamins and minerals
    • Production of bile, which aids in digestion and absorption of nutrients
    • Glycogen storage (involved in blood sugar regulation)
    • Synthesis of important proteins such as albumin and clotting factors
    • Red blood cell maintenance, in conjunction with the spleen

    How Do You Know If Your Dog's Liver Is Healthy?


    Many dogs do not show any outward signs of liver disease. Liver disease (elevated liver enzymes) may only be discovered in a laboratory test and/or a physical exam by your veterinarian.

    The following are signs of liver disease in dogs:


    • Loss of appetite
    • Jaundice (yellowing of the gums, whites of the eyes, or skin)
    • Vomiting or diarrhea
    • Changes in behavior (pacing, circling or even seizures)
    • Weight loss
    • Lack of energy
    • Ascites (buildup of fluid in the abdomen)

    Dogs with liver disease may also have gallbladder problems. Symptoms of an inflamed gallbladder or bile duct are similar to those produced by liver disease and can include a loss of appetite, jaundice and vomiting.




    Diagnosing Liver Disease in Dogs


    Liver disease in dogs can be caught early with regular blood work. It is important to have an annual physical exam and laboratory testing done at your vet, especially as your dog ages. Young dogs may have a congenital liver conditions such as microvascular dysplasia or a liver shunt and the symptoms may not be apparent until the pet is one or two years old. A blood test may be the only way to know.

    Elavated liver enzymes can indicate liver cell damage that has allowed enzymes to leak out of the liver and into the blood. High levels of the following enzymes may be seen in dogs with liver disease:


    • Alanine Aminotransferase (ALT) - An enzyme found in liver cells. When cells are damaged, ALT can leak into the blood.

    • Alkaline Phosphatase (ALKP) - An enzyme produced by the biliary tract (liver) that can be elevated when somehtng is damaging the liver. High levels can indicate bone disease, liver disease, Cushing's disease or bile flow blockage. Some ALKP elevation in older dogs is common.

    • Gamma Glutamyltransferase (GGT) - An enzyme produced in the liver, bile ducts, pancreas and kidneys. Elevations in GGT, especially along with elevations in alkaline phosphatase, can indicate impaired bile flow.

    • Total Bilirubin (TBIL) - Bilirubin is a yellowish brown byproduct from the breakdown of red blood cells. It gives color to jaundiced skin or eyes and to your dog's stool. Elevated bilirubin levels can be caused by a rapid destruction of red blood cells, a bile duct obstruction or liver damage.

    • Albumin (ALB) - Produced by the liver, albumin is a protein that helps control pressure in the tissues. When albumin is low, fluids can leak, resulting in a swollen abdomen. Low levels of albumin can indicate chronic liver or kidney disease, or parasitic infections. High levels indicate dehydration and loss of protein.

    A urine analysis and X-rays can provide valuable information as well. If signs and symptoms indicate a dog’s liver is not functioning optimally, additional tests, such as a bile acid test, ultrasound and/or liver biopsy, may be used to determine the underlying cause. Your veterinarian will recommend medications, diet changes and potential surgical procedures upon determining the cause of your dog’s liver disease.

    Bailey Rose

    "I just wanted to give you an update on my Yorkie Bailey Rose. Bailey Rose had high ALT levels and an abscess on her liver. Her last blood work before starting the Pancreatitis & Liver Support Kit showed liver enzymes 4 times what they should be and her WBC was 40,000. She continued on her antibiotics (for a bacterial infection) and started the Kit on Oct 1 as soon as I received it. I took her for her recheck yesterday (a few weeks later) and the vet called today and was amazed that all her levels including WBC were all in normal levels and after losing a pound she has got back to her normal weight! Even though she is almost 13 she is doing wonderful and acting like a puppy again. I also changed her food to the natural blend Ask Ariel suggested and she loves it. Thank you so much for helping me to help my sweet baby." - Cherie, Indiana



    Causes of Liver Disease in Dogs


    There are four main factors that increase the likelihood of your dog developing liver disease: age (more common in geriatrics), breed, obesity, and exposure to medications and/or chemicals. Conventional veterinary treatment for liver disease in pets depends on the cause of the illness. Common causes of liver disease in pets include:

    • Acute liver disease - due to an exposure to a toxic substance or excessive heat
    • Bile duct obstruction - result of inflammation or infection of the duct; gallbladder mucocele or cholecystitis
    • Hepatic lipidosis in cats - excessive accumulation of fat in the liver
    • Side effect of medications - long term use of antibiotics, steroids, parasiticides (flea and tick control), barbiturates (to control seizure activity), NSAIDs (nonsteroidal anti-inflammatory drugs)
    • Viral, bacterial, fungal, or parasitic infections

    Certain dog breeds are more likely to be born with or develop liver disease. These breeds include Dobermans, rottweilers, Maltese, Yorkshire terriers and cocker spaniels.

    Bedlington terriers, Dobermans, West Highland terriers, Skye terriers, and Labrador retrievers are more susceptible to copper-storage hepatopathy. This condition results from the abnormal accumulation of copper in the pet's liver. It can lead to cell damage, chronic inflammation (hepatitis) and scarring of the liver (cirrhosis).


    Miss Ladybug

    "I wanted to share with you that last year Miss Ladybug was diagnosed with a possible Gallbladder Mucocele and the vet put her on Ursodiol but it made her very sick, so instead she has been taking the Liver & Gallbladder Supplement, Power Probiotic, and LypoZyme everyday faithfully. We just had another ultrasound check and this time they said everything looks good, that they wouldn’t even say that it's a Mucocele anymore - it just looks like a gallbladder and hasn't gotten bigger. Her blood work was also wonderful - kidneys and liver (everything actually) were in range. Not bad for a 13 year old puppy mill rescue :) They did find a little irritation in the intestines that they feel could be IBD so I knew right away that I would be getting your Soothing Digestive Relief formula this time too. Thank you so much for your amazing products because I truly believe they have extended my baby's life!" - Marissa, Colorado






    Holistic Diet For Dogs With Liver Disease


    The best dog foods for liver disease are hypoallergenic, low fat diets that do not contain grains, chemical preservatives or artificial food colorings and dyes. A low-fat, fresh diet can be very beneficial. Vegetables can help naturally detoxify your pet's liver. Green vegetables contain not only valuable vitamins and minerals, but they also contain fresh enzymes and prebiotic fibers to cleanse the gut and support liver health. Colorful vegetables such as squash, carrots, and beets contain antioxidants and beta-carotene. Adding assorted vegetables such as asparagus, green beans, carrots, okra, leafy greens and a few shreds of grated raw beet can help improve your dog's digestion and liver health. Dandelion leaves contain Vitamin A, B, C, D and K, support blie flow and are a liver detoxifier, making them especially beneficial for pets with elevated liver enzymes. Omega 3s in the form of Amazing Omegas and baked fish are also helpful. Dogs with elevated liver enzymes fare best on a reduced-fat diet rich in fibrous vegetables and omega-3 fatty acids. Please include your dog’s diet and treats aon the order form at checkout and we will include free liver diet tips on the packing slip that comes with your order.


    Need Help?

    We understand how hard it is when your dog is suffering from liver disease and we will do all we can to help. It can be confusing to know which supplements would be appropriate for your pet. Please email us at Support@AskAriel.com. Please note that we cannot provide consultative advice due to veterinary regulations, but we will be happy to provide articles and information so that you can make an informed decision about what's best for your dog.

    Dog Liver Disease Frequently Asked Questions (FAQs)

    What is the best liver supplement for dogs?

    A high quality dog liver supplement should include natural ingredients such as milk thistle, SAMe, antioxidants and vitamins that help detoxify the liver. Ask Ariel’s dog liver supplements are made with ingredients that are scientifically proven to support liver function and promote cellular regeneration.

    How can liver supplements for dogs help?

    Natural dog liver supplements can help to detoxify the liver and support the liver as it regenerates healthy tissue. The liver cleans the body by removing harmful chemicals and waste products. When the liver becomes overloaded, toxins and waste can build up. This can cause many dogs with liver disease to have low energy and low appetite. Holistic dog liver treatments, especially when combined with a reduced fat, all natural diet can help repair and regenerate your pet’s liver cells.

    How can I detox my dog’s liver?

    High liver enzymes in dogs is quite common, but the liver is one of the few organs in the body that can regenerate healthy tissue. Detox your dog’s liver by using the best natural liver support supplements, feeding a liver friendly diet and reducing environmental toxins. Ask Ariel’s liver support supplements contain premium quality, human-grade ingredients that are scientifically proven to support both phases of liver detoxification. Our Liver & Gallbladder Support and Special SAMe (S-adenosylmethionine for dogs) are recommended by veterinarians nationwide because they are safe and effective products to detoxify your dog’s liver.

    What do you feed a dog with high liver enzymes?

    Pets with high liver enzymes and liver disease can show significant improvement when they are fed a liver-friendly diet and given the best natural liver support supplements for dogs. Many dog foods contain chemicals, allergens and grains which create additional work for the digestive system and liver. Pet treats may contain sugar, fillers and food dyes. A reduced fat diet with added omega-3 fatty acids (found in fish and fish oil) along with freshly steamed vegetables can be helpful for dogs with elevated liver enzymes or liver disease. Colorful root vegetables, such as beets and carrots, contain antioxidants and carotenoids (beta-carotene) which can help to stimulate bile flow and help eliminate wastes. At Ask Ariel, we will include free liver diet tips on the packing slip that comes with your order.

    How can SAMe and milk thistle support my dog’s liver?

    SAMe (S-Adenosyl-L-Methionine) and milk thistle are the most popular natural dog liver remedies to promote healthy liver function and support detoxification. Special SAMe is scientifically proven to reduce elevated liver enzymes. SAM-e also supplements metabolic activity by maintaining glutathione levels and supporting cell regeneration. Silymarin, the active ingredient in milk thistle, can prevent toxins from entering the liver, promotes cellular regeneration and improves liver function. Milk thistle contains anti-inflammatory and antioxidant properties and can help to support the immune system. Ask Ariel’s Liver & Gallbladder Support contains amino acids, Vitamin A, ox bile and inositol to promote fat metabolism and an herbal blend of milk thistle, artichoke and beet powder to support detoxification and improve bile flow. SAMe (S-Adenosyl-L-Methionine) and milk thistle have been recommended by holistic veterinarians nationwide to support liver function and detoxification.