Home > Shop By Condition > Cancer > Mast Cell Tumors In Dogs

Dog Mast Cell Tumors (MCT)

A mast cell tumor (also called mastocytomas or mast cell sarcomas) in dogs is most commonly found in the skin or subcutaneous tissue. Mast cells are a part of your pet's immune system and protect against parasitic invaders.

They are a type of white blood cell that contains histamine, heparin and enzymes involved in allergic reactions. Mast cell tumors are the most common skin tumors in dogs, accounting for nearly 20% of all skin tumors. While MCTs are primarily a skin cancer in dogs, they can metastasize to lymph nodes and other organs.

Causes of Mast Cell Tumors in Dogs

For most dogs, the underlying cause of a mast cell tumor is unknown. As with most cancers, it is probably due to a number of factors. There are genetic and environmental risk factors. Some dogs have a genetic protein mutation (receptor tyrosine kinase protein) that fuels the progression of mast cells.

The prognosis for dogs with MCTs depends on various factors: the grade of the tumor, its location, whether the MCT has spread and the success of the surgery in completely removing it. Mast cell tumors in dogs have a tendency to recur.

While there is no cure, MCTs can be managed by using a proactive holistic approach to support your dog's immunity and its ability to fight this type of cancer.

Mast Cell Tumor in Dogs Symptoms

Mast cell tumors can be found in any breed of dog but are most commonly found in Boston terriers, English bulldogs, Weimaraners, golden retrievers, pugs, beagles and boxers.

  • Unusual growth including skin tags or small bumps
  • Appearance of red, ulcerated or swollen patches of skin
  • Digestive problems including vomiting, lethargy, loss of appetite, and black, tarry stool
  • Skin rashes
  • Shortness of breath

Mast cell tumors in dogs can be found on the limbs, in between toes and in the spleen, liver and bone marrow.

Because they can look like all kinds of inflammatory lesions, pet owners may not notice them, and they can remain on a dog for a long time before they are treated. Please be sure to check your dog regularly for any unusual growths, and bring any lumps or bumps to the attention of your veterinarian, because early treatment will yield a much better outcome.

Diagnosis & Treatment of Mast Cell Tumors in Dogs

Mast cell tumors vary greatly in their size, shape, appearance and texture. An MCT in dogs is typically diagnosed by fine needle aspiration.

The only way to definitively identify them is with a biopsy and pathology report, which evaluates them based on location, grade and size. Mast cell tumors are one of the most treatable forms of cancer.

Surgery is generally recommended for both low- and high-grade tumors. In most cases of higher-grade tumors, chemotherapy is also recommended.

The Best Diet For Dogs With Mast Cell Tumors

Many dogs with mast cell tumors have a history of allergies.

Dogs with mast cell tumors need a low-carbohydrate, novel-protein diet and should avoid ingredients that can weaken immunity and increase the likelihood of another mast cell tumor recurring.

Ask Ariel has helped clients achieve exceptional results with MCTs, so be sure to include what you are feeding your dog on the order form at checkout. We will review your pet's information and include a FREE diet suggestion on the packing slip that comes with your order.

Supplements for Dogs with Mast Cell Tumors

If your dog is diagnosed with a mast cell tumor (MCT), a holistic approach with diet changes and supplements can be used along with conventional treatments prescribed by your veterinarian to support your dog's immune system and prevent recurrence.

MCT supplements can help control the histamine response and reduce inflammation, which reduces recurrences of mast cell tumors.

Natural Remedies for Canine Mast Cell Tumors

If your dog is diagnosed with a mast cell tumor (MCT), a holistic approach with diet changes and supplements can be used along with conventional treatments prescribed by your veterinarian to support your dog's immune system and prevent recurrence. Ask Ariel has extensive experience helping dogs with mast cell tumors using hypoallergenic, low-carbohydrate diets and natural supplements. MCT supplements for dogs (please see detailed information below) include: AllerEaze, Happy Paws Organic Hemp Extract CBD Oil, Immune Harmony, Amazing Omegas, Curcumin Complex for Pets and Resveratrol for Dogs. These products help control the histamine response, fight cancer and reduce inflammation, which reduces recurrences. Mast cell tumors have a high likelihood of recurring, so it is very important to try to help control recurrences using the appropriate diet and supplement regimen.

AllerEaze - AllerEaze is the first line of defense for dogs with mast cell tumors as it has been scientifically proven to naturally reduce a dog's histamine release. Mast cells are immune cells in the skin that respond to allergies and irritations in the skin. When they begin to multiply abnormally, they form a tumor. Mast cell tumors have high levels of histamine. Any manipulation of the tumor can cause a sudden release of histamine into the bloodstream. Veterinarians prescribe Benadryl to reduce the harmful effects of histamine on the pet. A sudden histamine release can cause swelling, vascular changes and inflammation. Quercetin is often considered nature's Benadryl, as it helps the body cope with the dangerous effects of excess histamine released by cancerous mast cells. AllerEaze can be used in addition to Benadryl to support a healthy immune response. AllerEaze in combination with Power Probiotic has been especially helpful for pets with mast cell tumors.

Power Probiotic - Power Probiotic is the best probiotic for pets! Backed by scientific research, this powerful multi-strain formula promotes the growth of good bacteria, supporting a healthy immune system. Probiotics are live microorganisms that live in different parts of your dog’s body such as the intestines, mouth, skin and sinus cavity. Good bacteria are not only essential for your dog’s digestive system but for their overall immune health. Probiotic supplements can reduce skin sensitivity and promote the balance of healthy bacteria on the skin to reduce inflammation. Power Probiotic is essential if your dog has taken antibiotics or steroids, which can kill off healthy bacteria, weakening your pet's immune response. Pure, safe and natural, Power Probiotic does not contain any fillers. Most pets love the taste!

Happy Paws Organic Hemp Extract For Dogs - A few drops of this professional veterinary strength CBD oil can help reduce inflammation and support a healthy immune system. Controlling inflammation is a core part of cancer treatment, and that is the main characteristic of this mast cell tumor dog CBD oil. The ingredients in Happy Paws are being researched for their beneficial effects on cancer. Anecdotal reports include reduced pain, inflammation and discomfort. Happy Paws is the best CBD oil for dog MCTs. It contains simple ingredients: organic hemp extract and coconut oil. It’s rigorously tested for potency and purity. Each 1oz bottle contains 550mg of full spectrum hemp extract in an unflavored all-natural coconut oil base. 100% organic. Made in the USA.

Immune Harmony - Immune Harmony is a premium-quality, patented blend of plant sterols and antioxidants. It’s the #1 choice for pets with cancer. This unique one-of-a-kind plant sterol supplement is tolerated well by even the smallest dogs. Inflammation can fuel tumor growth and cancer spread in pets. Immune Harmony helps to reduce inflammatory markers. This pet vitamin has been successfully used in conjunction with chemotherapy and/or prednisone since 2005. The sterols contained in Immune Harmony have been shown in studies to have anti-inflammatory, anti-cancer and immunomodulatory properties. No known toxicity has been found. The antioxidants protect the body from free radical damage, along with an essential fatty acid complex that assists in the bioavailability of these health-promoting nutrients. Excellent value: One bottle lasts between two to four months depending upon the weight of your dog.

OncoPet Cancer Vitamin - A broad-spectrum blend of herbs and medicinal mushrooms that provide powerful immune support. The natural ingredients in OncoPet contain polyphenols, beta-glucans and antioxidants, like D-fraction and L-ergothioneine, that boost the immune system and help regulate your dog's inflammatory response. OncoPet is a comprehensive dog cancer vitamin that also includes herbs to help balance the gut microbiome and reduce nausea and cancer-related fatigue. Combines well with MCT in dogs treatments from your veterinarian or veterinary oncologist. Helps pets handle chemotherapy and radiation. Excellent value. One bottle lasts up to 8 months for small dogs.

K9 CurcuMagic - K9 CurcuMagic contains all three curcuminoids along with turmeric essential oil for maximum effectiveness. This science-based antioxidant reduces oxidative damage from free radicals. K9 CurcuMagic is essential for dogs with cancer, as it supports a healthy immune response, has cancer-fighting properties and provides a critical antioxidant. Curcumin's benefit for cancer patients is being heavily researched and the cancer-fighting nutrients in this unique bioactive turmeric formula may help inhibit cancer tumor growth. Using a combination of K9 CurcuMagic and Resveratrol for Dogs as a PREVENTATIVE if you have a dog prone to mast cell tumors or cancer is an excellent strategy. K9 CurcuMagic absorbs best when digested with fat, especially omega-3 fatty acids (Amazing Omegas), which is why our clients use the two mast cell tumor supplements together. If your dog is undergoing radiation, curcumin can protect the skin.

Amazing Omegas - This is the highest-quality purified fish oil available for pets. It is a powerhouse of omega-3 fatty acids to help your dog fight cancer. The highly therapeutic amount of omega-3 fatty acids help to reduce inflammation. Omega-3s are critical for immune and nervous system function. Amazing Omegas is a purified fish oil made from sardines, anchovies and mackerel. Processed with minimal heat to preserve the oil in a highly bioavailable form, which means increased absorption. It's packed in glass bottles to prevent any chemicals from plastic leaching into the oil. Naturally processed with all toxins and heavy metals carefully removed. Scientific research has shown the benefits of omega 3s for pets with cancer. This supplement helps pets with allergies and skin problems too. Compare the nutrient panel of this premium pet fish oil to all other brands and see the difference.

Resveratrol for Dogs - Resveratrol is an exceptional antioxidant backed by research and can help your dog in so many ways. Resveratrol is a cancer support and preventative (use with dog breeds that have a higher incidence of cancer, such as bichon frises, German shepherds, Labradors, golden retrievers, boxers). It acts on the process of carcinogenesis by affecting all three phases - tumor initiation, promotion and progression - and suppresses the final steps of carcinogenesis. Resveratrol is cardio-protective (excellent for breeds prone to heart issues, such as Cavalier King Charles spaniels, poodles, dachshunds). Very important if your pet is undergoing radiation. Energizing, promotes longevity. Excellent for senior dogs. Resveratrol for Dogs also supports immune function.

What Our Customers Are Saying

Dunkin the Frenchie @dunkinthefrenchie

Dunkin has allergies and had a mast cell tumor removed. Ask Ariel products help to support his immune system and prevent recurrence. Here is what Dunkin's Mom said: "Great Customer Service and very knowledgeable on their products. We have been using Amazing Omegas for Pets, Power Probiotic and AllerEaze for about 3 years. We are super pleased with these products and they always arrive packaged well." - Diann, Georgia


"In January 2019, our 12-year-old mini-Schnauzer, Kaylee, developed a fatty lump on her upper right leg and lower chest area. Her doctor took some sample tissue and then diagnosed a grade 2 mast cell tumor. We scheduled removal within two weeks and she started a brief chemotherapy regimen. I began to research all-natural supplements for pets and found the Ask Ariel website. I was so glad to see affordable products specifically designed for pets. I found products that were recommended for dogs with mast cell tumors and read all of the reviews. I reached out to the customer support team and they were so helpful in answering questions regarding products. We started daily doses of Power Probiotic and AllerEaze. Her doctor continued to be amazed at how healthy she was following the tumor removal.

As Kaylee approached 14, she started getting up more at night and having cognitive issues. Plus, she was experiencing arthritis flare-ups that would make it uncomfortable for her to adjust her movements quickly. She would wake up howling out and trembling. We saw her doctor and she confirmed it was definitely a combination of cognitive issues and body aches associated with aging. Once again, I reached out to the incredible team at Ask Ariel. I added Special SAM-e and Happy Paws Drops to Kaylee's daily supplement regimen. Within just a few days, Kaylee was sleeping comfortably through the night. She was also her active self, leaping up and down off of beds and furniture...following her little human sisters everywhere they went...especially if there was food in sight.

This past January, I noticed a sudden lump right on her neck, right above her left shoulder area. Her vet took a sample and confirmed another mast cell tumor. After removal, her doctor told me that this one was more aggressive than the one that was removed three years earlier. Kaylee actually lost part of her upper muscle, due to the growth being attached to a portion of it. Her doctor told me that she would have limited mobility on that side. We brought her home and she immediately ran to the pantry for a treat! Within an hour, she was chasing kids through the house. It's now been three months since that growth removal and she is still as active as ever. Kaylee can jump up on the couch, bed, recliner...where ever she sees a cozy spot...or someone enjoying a snack! Our family is so grateful for our time with Kaylee, during her senior years. At 15 1/2 years old, she is still such a playful pup. We are also so thankful for the quality products from Ask Ariel. Using these supplements on a regular basis has greatly increased Kaylee's quality of life." - Cynthia, Louisiana

Boston Terrier With Mast Cell Tumors Is Doing Great Years Later

"My precious Boston Terrier, Marcie had 3 mast cell tumors removed at age 7. One of the tumors had become a grade 2. After reading the pathology report and various other articles, I was terrified of what might happen. MCT is common for Boston Terriers. She's my baby and I will do anything I can to give her the best and all she needs.

I ordered several products from the Ask Ariel website which I have been using for several years now. Other than a couple of changes in protein sources, which is necessary with dogs with serious allergies, my baby is amazing. Everybody that meets her is in awe of her beauty and comment on the glow of her coat which I attribute to Amazing Omegas. They cannot believe that she is nine years old and has puppy energy!

I thank God each day He gives me to love her. Marcie's recent bloodwork results were awesome. I know it would not be possible without Ask Ariel's help. I highly recommend their expertise and products." - Kim, Florida

Some Of The Products Marcie Used: Amazing Omegas for Pets, Resveratrol For Dogs, AllerEaze, K9 Digestive Enzymes and Immune Harmony.

Shop Dog Mast Cell Tumor Supplements

Sort By:
Page of 1
natural anti inflammatory for dogs K9 CurcuMagic For Dogs
Our Price: $45.95
Sale Price: $38.95
Savings: $7.00
OncoPet Cancer Vitamin OncoPet Cancer Vitamin
Our Price: $54.95
Sale Price: $44.95
Savings: $10.00
Resveratrol for Dogs Resveratrol for Dogs
Our Price: $64.75
Sale Price: $52.75
Savings: $12.00
Happy Paws Drops Happy Paws Drops
Our Price: $64.50
Sale Price: $54.50
Savings: $10.00
Immune Harmony Immune Harmony
Our Price: $69.75
Sale Price: $54.75
Savings: $15.00
Originally published Dec 11, 2023
Updated May 16, 2024
Written by: Susan Davis, Pet Health Nutritionist, CCN
All pet treatment protocols and pet treatment supplements have been reviewed and approved by a veterinarian